The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 23, 2011

Filed:

Nov. 10, 2006
Applicants:

James C. Barrow, Harleysville, PA (US);

Kenneth E. Rittle, Green Lane, PA (US);

Phung Le Bondiskey, Lansdale, PA (US);

Inventors:

James C. Barrow, Harleysville, PA (US);

Kenneth E. Rittle, Green Lane, PA (US);

Phung Le Bondiskey, Lansdale, PA (US);

Assignee:

Merck. Sharp & Dohme Corp., Rahway, NJ (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/496 (2006.01); A61K 31/4439 (2006.01); A61K 31/4166 (2006.01); C07D 403/12 (2006.01); C07D 401/12 (2006.01); C07D 235/02 (2006.01); C07D 233/32 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention is directed to imidazolidinone compounds which are inhibitors of the beta-secretase enzyme and that are useful in the treatment of diseases in which the beta-secretase enzyme is involved, such as Alzheimer's disease. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the treatment of such diseases in which the beta-secretase enzyme is involved.


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