The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 23, 2011
Filed:
Feb. 06, 2008
Masaki Meguro, Tokyo, JP;
Tomichiro Oda, Tokyo, JP;
Yasuhiro Nakagami, Tokyo, JP;
Shinji Marumoto, Tokyo, JP;
Kazuo Koyama, Tokyo, JP;
Isao Kaneko, Tokyo, JP;
Masaki Meguro, Tokyo, JP;
Tomichiro Oda, Tokyo, JP;
Yasuhiro Nakagami, Tokyo, JP;
Shinji Marumoto, Tokyo, JP;
Kazuo Koyama, Tokyo, JP;
Isao Kaneko, Tokyo, JP;
BTG International Ltd., London, GB;
Abstract
The present invention relates to preventives or remedies for Alzheimer's disease, or to amyloid protein fibril-formation inhibitors, which include as an active ingredient a compound of general formula (I) below or a pharmacologically permitted salt thereof; and also to nitrogen-containing heteroaryl derivatives having specific substituents, or pharmacologically permitted salts thereof, which are valuable as preventives or remedies for Alzheimer's disease, or as amyloid protein fibril-formation inhibitors: (where, Rand Rare H or alkyl; Zand Zare H, alkyl, alkoxy, haloalkyl or halogeno; Zis alkoxy, SH, alkylthio, NH, mono- or di-alkylamino, OH or halogeno; Zand Zare H or halogeno; and A is 4,6-pyrimidine-1,3-diyl, 1,3,5-triazine-2,6-diyl, etc).