The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 23, 2011
Filed:
Apr. 13, 2005
Arie Ben-bassat, Newark, DE (US);
Fateme Sima Sariaslani, Wilmington, DE (US);
Lisa L. Huang, Hockessin, DE (US);
Ranjan Patnaik, Newark, DE (US);
David J. Lowe, Wilmington, DE (US);
Arie Ben-Bassat, Newark, DE (US);
Fateme Sima Sariaslani, Wilmington, DE (US);
Lisa L. Huang, Hockessin, DE (US);
Ranjan Patnaik, Newark, DE (US);
David J. Lowe, Wilmington, DE (US);
E. I. du Pont de Nemours and Company, Wilmington, DE (US);
Abstract
Methods for the microbial production of para-hydroxycinnamic acid (pHCA) and cinnamic acid (CA) are provided. Microbes producing either tyrosine or phenylalanine are grown in the presence of either tyrosine ammonium lyase or phenylalanine ammonium lyase respectively where some part of the fermentation is accomplished at alkaline pH. The process results in greater yields and higher rates of para-hydroxycinnamic acid (pHCA) and cinnamic acid (CA) production as compared with fermentation exclusively at physiological pH.