The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 23, 2011
Filed:
Nov. 30, 2007
Jeong-nam Park, Daejeon, KR;
Yunkyoung Song, Daejeon, KR;
Jeong-yoon Kim, Daejeon, KR;
Doo-byoung OH, Daejeon, KR;
Hyun Ah Kang, Daejeon, KR;
Jeong-Nam Park, Daejeon, KR;
Yunkyoung Song, Daejeon, KR;
Jeong-Yoon Kim, Daejeon, KR;
Doo-Byoung Oh, Daejeon, KR;
Hyun Ah Kang, Daejeon, KR;
Korea Research Institute of Bioscience and Biotechnology, Daejeon, KR;
Abstract
The present invention relates to a novel YlMPO1 gene which plays an important role in mannosylphosphorylation of an industrial yeastand to a method for preparing a host system capable of producing recombinant glycoproteins free of mannosylphosphate by disruption of the gene. The mannosylphosphorylation is suppressed by the disruption of YlMPO1 gene according to the present invention, thereby achieving humanization of glycosylation pathway of