The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 23, 2011
Filed:
Sep. 29, 2009
Johannes Auer, Schwaigen, DE;
Nikolaos Dimoudis, Wielenbach, DE;
Guy Georges, Habach, DE;
Petra Hanke, Munich, DE;
Hendrik Knoetgen, Penzberg, DE;
Ekkehard Moessner, Kreuzlingen, CH;
Claire Louise Langrish, Palo Alto, CA (US);
Johannes Auer, Schwaigen, DE;
Nikolaos Dimoudis, Wielenbach, DE;
Guy Georges, Habach, DE;
Petra Hanke, Munich, DE;
Hendrik Knoetgen, Penzberg, DE;
Ekkehard Moessner, Kreuzlingen, CH;
Claire Louise Langrish, Palo Alto, CA (US);
Roche Palo Alto LLC, Palo Alto, CA (US);
Abstract
An antibody binding to IL-17 characterized by binding to the same IL-17 epitope to which monoclonal antibody 3C1 binds, and being of human IgG1 isotype modified in the hinge region at amino acid position 216-240, preferably at amino acid position 220-240, between C1 and C2 and/or in the second inter-domain region at amino acid position 327-331 between C2 and C3 has advantageous properties for the treatment of inflammatory diseases.