The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 23, 2011
Filed:
Feb. 22, 2007
Shuichi Nakatsuru, Kanagawa, JP;
Megumi Yoshikawa, Kanagawa, JP;
Shinichi Hiroshima, Kanagawa, JP;
Yoshiro Kishi, Aichi, JP;
Motoki Kuhara, Aichi, JP;
Shiyo Nishida, Aichi, JP;
Midori Shinohara, Aichi, JP;
Shuichi Nakatsuru, Kanagawa, JP;
Megumi Yoshikawa, Kanagawa, JP;
Shinichi Hiroshima, Kanagawa, JP;
Yoshiro Kishi, Aichi, JP;
Motoki Kuhara, Aichi, JP;
Shiyo Nishida, Aichi, JP;
Midori Shinohara, Aichi, JP;
Oncotherapy Science, Inc., , JP;
Abstract
The present invention relates to the use of cytoxicity based on the effector function of anti-EphA4 antibodies. Specifically, the present invention provides methods and pharmaceutical compositions that comprise an anti-EphA4 antibody as an active ingredient for damaging EphA4-expressing cells using antibody effector function. Since EphA4 is strongly expressed in pancreatic cancer cells, the present invention is particularly useful in pancreatic cancer therapies.