The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 23, 2011
Filed:
Mar. 29, 2007
Gregory M. Lanza, St. Louis, MO (US);
Samuel A. Wickline, St. Louis, MO (US);
Garry E. Kiefer, Richardson, TX (US);
Phillip S. Athey, Lake Jackson, TX (US);
Gregory M. Lanza, St. Louis, MO (US);
Samuel A. Wickline, St. Louis, MO (US);
Garry E. Kiefer, Richardson, TX (US);
Phillip S. Athey, Lake Jackson, TX (US);
Barnes-Jewish Hospital, St. Louis, MO (US);
Abstract
MRI contrast agents that employ paramagnetic agents and chemical exchange saturation transfer (paraCEST) and which are coupled to targeted particulate delivery vehicles provide sufficient concentration of the paraCEST contrast agents to obtain useful images of target tissues or organs. In addition, the image contrast may be switched on or off with a presaturation radio frequency pulse, avoiding the necessity obtaining pre-injection and post-injection images.