The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 16, 2011
Filed:
Mar. 03, 2006
Michael Milburn, Cary, NC (US);
Jill Milne, Brookline, MA (US);
Jean Bemis, Arlington, MA (US);
Joseph J. Nunes, Andover, MA (US);
Roger Xie, Southborough, MA (US);
Karl D. Normington, Acton, MA (US);
Chi B. VU, Arlington, MA (US);
Michael Milburn, Cary, NC (US);
Jill Milne, Brookline, MA (US);
Jean Bemis, Arlington, MA (US);
Joseph J. Nunes, Andover, MA (US);
Roger Xie, Southborough, MA (US);
Karl D. Normington, Acton, MA (US);
Chi B. Vu, Arlington, MA (US);
Sirtris Pharmaceuticals, Inc., Cambridge, MA (US);
Abstract
Provided herein are novel sirtuin-modulating compounds and methods of use thereof. The sirtuin-modulating compounds may be used for increasing the lifespan of a cell, and treating and/or preventing a wide variety of diseases and disorders including, for example, diseases or disorders related to aging or stress, diabetes, obesity, neurodegenerative diseases, chemotherapeutic induced neuropathy, neuropathy associated with an ischemic event, polyglutamine diseases, ocular diseases and/or disorders, cardiovascular disease, blood clotting disorders, inflammation, cancer, and/or flushing. Also provided are compositions comprising a sirtuin-modulating compound in combination with another therapeutic agent.