The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 16, 2011
Filed:
Oct. 08, 2008
Applicants:
Douglas Cines, Wynnewood, PA (US);
Khalil Bdeir, Jenkintown, PA (US);
Klaus T. Preissner, Glessen, DE;
Triantafylios Chavakis, Chevy Chase, MD (US);
Inventors:
Douglas Cines, Wynnewood, PA (US);
Khalil Bdeir, Jenkintown, PA (US);
Klaus T. Preissner, Glessen, DE;
Triantafylios Chavakis, Chevy Chase, MD (US);
Assignee:
The Trustees of the University of Pennsylvania, Philadelphia, unknown;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
Abstract
The present invention relates to the inhibition of angiogenesis by neutrophil alpha-defensins. Further, the present invention relates to methods involving the inhibition of endothelial cell adhesion to the extracellular matrix, endothelial cell apoptosis, and endothelial cell angiogenesis mediated by alpha-defensins.