The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 16, 2011
Filed:
Oct. 26, 2007
Gregory Thoorens, Brussels, BE;
Bruno Leclercq, Brussels, BE;
Brian Carlin, Lawrenceville, NJ (US);
Peter J. Riley, Yardley, PA (US);
Miguel Angel Garcia, Newark, DE (US);
Gregory Thoorens, Brussels, BE;
Bruno Leclercq, Brussels, BE;
Brian Carlin, Lawrenceville, NJ (US);
Peter J. Riley, Yardley, PA (US);
Miguel Angel Garcia, Newark, DE (US);
FMC Corporation, Philadelphia, PA (US);
Abstract
A method for the preparation of microcrystalline cellulose containing tablets by roller compaction followed by tabletting is disclosed. A tablet formulation is converted to a dry granulate by roller compaction, and the dry granulate is lubricated and compacted to a tablet. The tablet formulation comprises at least one active, an microcrystalline cellulose containing material, and, optionally other pharmaceutically acceptable excipients. The microcrystalline cellulose containing material has a maximum primary compaction tensile strength of at least 9 MPa or at least 9.5 MPa and a secondary compaction tensile strength of at least 5 MPa, at least 5.5 MPa, or at least 6 MPa. A method for evaluating binders is also disclosed.