The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 16, 2011
Filed:
Dec. 19, 2003
Kirill Yakovlevsky, Cambridge, MA (US);
Michael Shamashkin, Somerville, MA (US);
Nazer Khalaf, Worcester, MA (US);
Chandrika P. Govardhan, Lexington, MA (US);
Chu W. Jung, Arlington, MA (US);
Kirill Yakovlevsky, Cambridge, MA (US);
Michael Shamashkin, Somerville, MA (US);
Nazer Khalaf, Worcester, MA (US);
Chandrika P. Govardhan, Lexington, MA (US);
Chu W. Jung, Arlington, MA (US);
Althea Technologies Inc., San Diego, CA (US);
Abstract
This invention relates to SPPs, spherical nanocrystalline composite particles or crystalline SPPs of biologically active proteins or compositions, including formulations, comprising such SPPs, spherical nanocrystalline composite particles or crystalline SPPs. More particularly, methods are provided for the production of SPPs, spherical nanocrystalline composite particles or crystalline SPPs of high concentrations of biologically active proteins, and for the preparation of stabilized SPPs, spherical nanocrystalline composite particles or crystalline SPPs for use alone, or in dry or slurry compositions. This invention also relates to methods for stabilization, storage and delivery of biologically active proteins using SPPs, spherical nanocrystalline composite particles or crystalline SPPs. The present invention further relates to methods using SPPs, spherical nanocrystalline composite particles or crystalline SPPs, or compositions or formulations comprising such SPPs, spherical nanocrystalline composite particles or crystalline SPPs, for biomedical applications, including biological delivery to humans and animals.