The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 09, 2011

Filed:

Apr. 03, 2009
Applicants:

Chung-yang Huang, Taipei, TW;

Chia-nan Chen, Taipei, TW;

Wei-jan Huang, Taipei, TW;

Chia-wei Lin, Taipei, TW;

Jing-shi Huang, Taipei, TW;

Li-ling Chi, Taipei, TW;

Ai-ling Chen, Taipei, TW;

Chi-yun Lee, Taipei, TW;

Yu-chen Huang, Taipei, TW;

Inventors:

Chung-Yang Huang, Taipei, TW;

Chia-Nan Chen, Taipei, TW;

Wei-Jan Huang, Taipei, TW;

Chia-Wei Lin, Taipei, TW;

Jing-Shi Huang, Taipei, TW;

Li-Ling Chi, Taipei, TW;

Ai-Ling Chen, Taipei, TW;

Chi-Yun Lee, Taipei, TW;

Yu-Chen Huang, Taipei, TW;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07C 303/00 (2006.01); C07C 313/00 (2006.01); C07C 259/04 (2006.01); C07D 307/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention relates to a compound represented by the following formula (I): and pharmaceutically acceptable salts, stereoisomers, enantiomers, prodrugs and solvates thereof. The compounds are useful as an agent for enhancing the neurite outgrowth and preventing or treating of diseases associated with HDAC in particular, tumor or cell proliferative diseases. In particular, the compounds of the invention can be used as an agent for anti-cancer, anti-diabetic, and anti-neurodegenerative diseases such as Alzheimer's disease, Huntington's disease, Spinocerebellar Ataxias (SCA), and human spinal muscular atrophy (SMA).


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