The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 09, 2011
Filed:
Jan. 14, 2005
Applicants:
Wei-ping Chen, Liverpool, GB;
John Whittall, Lancaster, GB;
Inventors:
Wei-Ping Chen, Liverpool, GB;
John Whittall, Lancaster, GB;
Assignee:
Solvias AG, Basel, CH;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07F 15/02 (2006.01); C08F 4/70 (2006.01); C08F 4/80 (2006.01);
U.S. Cl.
CPC ...
Abstract
The present invention relates to metallocene-based phosphine ligands having chirality at phosphorus and at least one other element of chirality (planar chirality and/or chirality at carbon); and to the use of such ligands in asymmetric transformation reactions to generate high enantiomeric excesses of formed compounds. A method for the preparation of ligands according to the invention involving the conversion of the ortho-lithiated substituted metallocene to a phosphine chiral at phosphorus is also disclosed.