The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 09, 2011
Filed:
Dec. 06, 2004
Vicente R. Tur, Barcelona, ES;
Albert Martinus Van Der Sloot, Barcelona, ES;
Margaret M. Mullally, Utrecht, NL;
Robbert H. Cool, Groningen, NL;
Eva E. Szegezdi, Galway, IE;
Afshin Samali, Galway, IE;
Gregorio Fernandez-ballester, Elche, ES;
Luis Serrano, Barcelona, ES;
Wilhelmus J. Quax, Kropswolde, NL;
Vicente R. Tur, Barcelona, ES;
Albert Martinus Van der Sloot, Barcelona, ES;
Margaret M. Mullally, Utrecht, NL;
Robbert H. Cool, Groningen, NL;
Eva E. Szegezdi, Galway, IE;
Afshin Samali, Galway, IE;
Gregorio Fernandez-Ballester, Elche, ES;
Luis Serrano, Barcelona, ES;
Wilhelmus J. Quax, Kropswolde, NL;
European Molecular Biology Laboratory, Heidelberg, DE;
National University of Ireland, Galway, IE;
University of Groningen, Groningen, NL;
Abstract
The present invention relates to novel methods for the design of proteins, in particular, cytokines. These methods allow the stabilisation of such cytokines, as well as modification of their selectivity/specificity for their cognate receptors. The invention also relates to various modified proteins that have been designed by the methods of the invention.