The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 09, 2011

Filed:

Feb. 06, 2007
Applicants:

Naoya Ono, Toshima-ku, JP;

Tetsuo Takayama, Toshima-ku, JP;

Fumiyasu Shiozawa, Toshima-ku, JP;

Hironori Katakai, Toshima-ku, JP;

Tetsuya Yabuuchi, Toshima-ku, JP;

Tomomi Ota, Toshima-ku, JP;

Takeshi Koami, Toshima-ku, JP;

Rie Nishikawa, Toshima-ku, JP;

Inventors:

Naoya Ono, Toshima-ku, JP;

Tetsuo Takayama, Toshima-ku, JP;

Fumiyasu Shiozawa, Toshima-ku, JP;

Hironori Katakai, Toshima-ku, JP;

Tetsuya Yabuuchi, Toshima-ku, JP;

Tomomi Ota, Toshima-ku, JP;

Takeshi Koami, Toshima-ku, JP;

Rie Nishikawa, Toshima-ku, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4152 (2006.01); A61K 31/4166 (2006.01); A61K 31/4168 (2006.01); A61K 31/4155 (2006.01); A61K 31/4178 (2006.01); A61K 31/4439 (2006.01); A61K 31/4709 (2006.01); A61K 31/5377 (2006.01); C07D 233/70 (2006.01); C07D 413/12 (2006.01); C07D 403/12 (2006.01); C07D 413/14 (2006.01); C07D 215/36 (2006.01); C07D 401/12 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention aims to provide compounds which have an inhibitory effect on the binding between S1P and its receptor Edg-1(S1P) and which are useful for pharmaceutical purposes. A compound represented by formula (I) or a pharmaceutically acceptable salt thereof: [wherein Ar represents a monocyclic heterocyclic ring containing one or two nitrogen atoms, A represents an oxygen atom or the like, Y, Yand Yeach represent a carbon atom or a nitrogen atom, Rrepresents a hydrogen atom, a C-Calkyl group or the like, Rrepresents a C-Calkyl group, a C-Ccycloalkyl group or the like, Rrepresents a C-Calkyl group or the like, Rrepresents a hydrogen atom or a C-Calkyl group, and Rrepresents a C-Calkyl group or the like].


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