The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 09, 2011
Filed:
Apr. 30, 2004
Balázs Sümegi, Pécs, HU;
Kálmán Hideg, Pécs, HU;
Tamás Kálai, Pécs, HU;
Pecsi Tudomanyegyetem, Pecs, HU;
Abstract
The subject of the present invention are quinazoline derivatives and their pharmaceutically acceptable salts of general formula (I), that inhibit a DNA-repairing enzyme, poly(ADP-ribose) polymerase (PARP), enabling them to be used for the preparation of pharmaceutical compositions for preventing or treating illnesses where PARP-inhibition yields a beneficial effect. In general formula (I) Rstands for either hydrogen or a group of general formula (a); Rstands for a) hydrogen or Calkyl group, if Ris other than hydrogen, and b) if Ris hydrogen, then Rmay be a group of general formula (b), (c) or (d). The subject of the present invention also embraces the preparation processes of the compounds described above.