The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 09, 2011

Filed:

Apr. 24, 2007
Applicants:

Renhua LI, Fishers, IN (US);

Thomas Edward Mabry, Indianapolis, IN (US);

Owen Brendan Wallace, Westfield, IN (US);

Leonard Larry Winneroski, Jr., Greenwood, IN (US);

Yanping Xu, Noblesville, IN (US);

Inventors:

Renhua Li, Fishers, IN (US);

Thomas Edward Mabry, Indianapolis, IN (US);

Owen Brendan Wallace, Westfield, IN (US);

Leonard Larry Winneroski, Jr., Greenwood, IN (US);

Yanping Xu, Noblesville, IN (US);

Assignee:

Eli Lilly and Company, Indianapolis, IN (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/496 (2006.01); A61K 31/454 (2006.01); C07D 403/02 (2006.01); C07D 401/14 (2006.01); C07D 401/04 (2006.01); C07D 207/26 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention discloses novel compounds of Formula I: having 11 Beta-HSD type 1 antagonist activity, as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising compounds of Formula I, as well as methods of using the compounds and compositions to treat diabetes, hyperglycemia, obesity, hypertension, hyperlipidemia, metabolic syndrome, and other conditions associated with 11 Beta-HSD type 1 activity. X-17377


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