The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 09, 2011
Filed:
Mar. 10, 2004
Applicants:
Yuji Yamamoto, Tsukuba, JP;
Tatsuo Watanabe, Inzai, JP;
Masayuki Okada, Tsukuba, JP;
Akihiko Tsuruoka, Tsukuba, JP;
Inventors:
Yuji Yamamoto, Tsukuba, JP;
Tatsuo Watanabe, Inzai, JP;
Masayuki Okada, Tsukuba, JP;
Akihiko Tsuruoka, Tsukuba, JP;
Assignee:
Eisai R&D Management Co., Ltd., Tokyo, JP;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/33 (2006.01); A01N 43/00 (2006.01);
U.S. Cl.
CPC ...
Abstract
It was discovered that a compound represented by the general formula (I) shows strong c-Kit kinase inhibitory activity, and it inhibits proliferation of c-Kit kinase activated-cancer cells in vitro and in vivo. A novel anticancer agent showing c-Kit kinase inhibitory activity was discovered. The general formula (I): (wherein Rrepresents methyl etc., Rrepresents cyano etc., Rrepresents hydrogen etc., Rrepresents hydrogen etc.).