The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 09, 2011

Filed:

Oct. 09, 2009
Applicants:

Makoto Koizumi, Kanagawa, JP;

Koji Morita, Tokyo, JP;

Inventors:

Makoto Koizumi, Kanagawa, JP;

Koji Morita, Tokyo, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 48/00 (2006.01); C07H 21/02 (2006.01);
U.S. Cl.
CPC ...
Abstract

A method of treating a tumor or a viral disease by administering to a human the following 2',5′-oligoadenylate analog: Wherein m is 0; n is 0 or 1; Ris alkoxy substituted by hydroxyl, mercapto, alkylthio substituted by hydroxyl or X—X—X—S—; R, R, R, Rand Rare hydroxyl, mercapto, alkylthio substituted by hydroxyl or X—X—X—S—; Ris oxygen, sulfur, —NH—, or —O(CHCHO)q-, wherein q is 2 to 6, or oxyalkyleneoxy; Ris hydrogen or a 5′-phosphorylated oligonucleotide which has one hydroxyl removed from the 5′-phosphoric acid; Eis K; Eis K; Eis Kor Kand Eis K, Kor K; Kis Kis Kis B is adeninyl; A is alkylene;D is alkyl or alkenyl; Xis alkyl or phenyl; Xis —C(═O)O—, —OC(═O)— or —C(═O)S—; and Xis alkylene.


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