The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 09, 2011

Filed:

Mar. 29, 2006
Applicants:

Ahmed Merzouk, Richmond, CA;

Abdelkrim Habi, Dollard-Des-Ormeaux, CA;

Donald Wong, Vancouver, CA;

Hassan Salari, Delta, CA;

Inventors:

Ahmed Merzouk, Richmond, CA;

Abdelkrim Habi, Dollard-Des-Ormeaux, CA;

Donald Wong, Vancouver, CA;

Hassan Salari, Delta, CA;

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); A61K 31/70 (2006.01); A61K 45/00 (2006.01); A61K 48/00 (2006.01); C07K 14/00 (2006.01); C12Q 1/00 (2006.01); G01N 63/00 (2006.01); C12N 15/63 (2006.01); C12N 5/08 (2006.01); A01N 63/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present disclosure generally teaches compositions comprising SDF-1 mimetics and methods of using them to modulate an activity of a cell having an SDF-1 receptor by binding the SDF-1 receptor to an SDF-1 mimetic. The cell can be a hematopoietic cell, for example, and can be selected from a group consisting of hematopoietic stem cells, hematopoietic progenitor cells, primitive granulocytes, primitive erythroid cells, leukocytes, and neutrophils. In some embodiments, the activity can include the rate of multiplication of the cell or, where the cell is a quiescent cell, the binding can repress the activation of the quiescent cell. Other embodiments of the present invention are taught herein.


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