The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 09, 2011
Filed:
Dec. 19, 2001
Johan Fährenmark, Sollentuna, SE;
Inger Lagerlund, Bromma, SE;
Robert Morenweiser, Regensburg, DE;
Mylene Caussette, Lille, FR;
Eric Piron, Lambersart, FR;
Johan Fährenmark, Sollentuna, SE;
Inger Lagerlund, Bromma, SE;
Robert Morenweiser, Regensburg, DE;
Mylene Caussette, Lille, FR;
Eric Piron, Lambersart, FR;
GE Healthcare Bio-Sciences AB, Uppsala, SE;
DSM IP Assets BV, Te Heerlen, NL;
Abstract
We describe a method for purifying chymosin comprising providing an aqueous liquid sample containing chymosin and a separation medium comprising a base matrix and a plurality of firmly attached ligands that are capable of binding to chymosin, contacting the matrix with the sample under conditions permitting binding of chymosin to the matrix, and desorbing chymosin from the matrix. The characterizing feature is that the matrix is hydrophilic and that the ligands in the plurality of ligands are hydrocarbon groups in which all carbon atoms are sp-hybridised, possibly with an ether oxygen or a thioether sulphur inserted between two carbon atoms at one or more positions in at least one of the hydrocarbon groups, and possibly a hydroxy group replacing a hydrogen atom at one or more positions in at least one of the hydrocarbon groups.