The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 02, 2011

Filed:

Feb. 02, 2009
Applicants:

Zhe Yang, Daly City, CA (US);

Scott Collibee, San Carlos, CA (US);

Alex R. Muci, San Francisco, CA (US);

Jianchao Wang, Foster City, CA (US);

Luke W. Ashcraft, San Francisco, CA (US);

Jeff Gardina, Santa Clara, CA (US);

Brian Stoltz, San Marino, CA (US);

Gustave Bergnes, Pacifica, CA (US);

Bradley P. Morgan, Moraga, CA (US);

Inventors:

Zhe Yang, Daly City, CA (US);

Scott Collibee, San Carlos, CA (US);

Alex R. Muci, San Francisco, CA (US);

Jianchao Wang, Foster City, CA (US);

Luke W. Ashcraft, San Francisco, CA (US);

Jeff Gardina, Santa Clara, CA (US);

Brian Stoltz, San Marino, CA (US);

Gustave Bergnes, Pacifica, CA (US);

Bradley P. Morgan, Moraga, CA (US);

Assignee:

Cytokinetics, Incorporated, South San Francisco, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/437 (2006.01); C07D 471/04 (2006.01); A61P 25/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

Provided are certain chemical entities, and methods of use to modulate skeletal myosin, skeletal actin, skeletal tropomyosin, skeletal troponin C, skeletal troponin I, skeletal troponin T, and skeletal muscle, including fragments and isoforms thereof, as well as the skeletal sarcomere, and methods of use in the treatment of neuromuscular disorders, conditions having muscle wasting, claudication, frailty, metabolic syndrome, muscle atrophy associated with disuse, and muscle fatigue, and other indications.


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