The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 02, 2011
Filed:
Sep. 06, 2004
Jamal Tazi, Clapiers, FR;
Johann Soret, Teyran, FR;
Philippe Jeanteur, Montferrier, FR;
David Grierson, Versailles, FR;
Christian Rivalle, Paris, FR;
Emile Bisagni, Orsay, FR;
Chi Hung Nguyen, Antony, FR;
Jamal Tazi, Clapiers, FR;
Johann Soret, Teyran, FR;
Philippe Jeanteur, Montferrier, FR;
David Grierson, Versailles, FR;
Christian Rivalle, Paris, FR;
Emile Bisagni, Orsay, FR;
Chi Hung Nguyen, Antony, FR;
Centre National de la Recherche Scientifique (CNRS), , FR;
Universite Montpellier II, , FR;
Institut Curie, , FR;
Abstract
The invention relates to indole-derived compounds and to the use of said compounds for the preparation of a medicament that can be used to treat diseases related to the process of splicing pre-messenger RNAs in the cell, such as Frasier syndrome, frontotemporal dementia linked to chromosome 17 (a form of Parkinson's disease), Leigh syndrome (a type of encephalopathy), atypical cystic fibrosis, certain neuropathologies including Alzheimer's disease linked to a mutation in the Tau protein, muscle atorphy which affects the SMN (Survival of Motor Neuron) gene, depression linked to a serotonin splicing impairment, and certain cancers in which the global splicing process is affected (e.g. breast cancer, colon cancer and certain lymphomas), as well as viral diseases such as AIDS.