The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 02, 2011

Filed:

Mar. 31, 2006
Applicants:

Michael Patrick Hay, Auckland, NZ;

Adrian Blaser, Auckland, NZ;

William Alexander Denny, Auckland, NZ;

Kevin Owen Hicks, Auckland, NZ;

Ho Huat Lee, Auckland, NZ;

Karin Pchalek, Auckland, NZ;

Frederik Bastiaan Pruijn, Auckland, NZ;

Bronwyn Gae Siim, Auckland, NZ;

William Robert Wilson, Waiuku, NZ;

Shangjin Yang, Auckland, NZ;

Inventors:

Michael Patrick Hay, Auckland, NZ;

Adrian Blaser, Auckland, NZ;

William Alexander Denny, Auckland, NZ;

Kevin Owen Hicks, Auckland, NZ;

Ho Huat Lee, Auckland, NZ;

Karin Pchalek, Auckland, NZ;

Frederik Bastiaan Pruijn, Auckland, NZ;

Bronwyn Gae Siim, Auckland, NZ;

William Robert Wilson, Waiuku, NZ;

Shangjin Yang, Auckland, NZ;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A01N 43/64 (2006.01); A01N 43/62 (2006.01); A61K 31/53 (2006.01); A61K 31/55 (2006.01); C07D 253/08 (2006.01); C07D 487/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention relates to novel tricyclic 1,2,4-triazine-1-oxides and novel tricyclic 1,2,4-triazine-1,4-dioxides of formula I and to related analogues, to their preparation, and to their use as hypoxia-selective drugs and radiosensitizers for cancer therapy, both alone or in combination with radiation and/or other anticancer drugs.


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