The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 02, 2011

Filed:

Jul. 07, 2005
Applicants:

Sybille Ebert, Biberach, DE;

Hans-peter Hohnmann, Loerrach, DE;

Martin Lehmann, Grenzach-Wyhlen, DE;

Nigel John Mouncey, Binningen, CH;

Markus Wyss, Liestal, CH;

Inventors:

Sybille Ebert, Biberach, DE;

Hans-Peter Hohnmann, Loerrach, DE;

Martin Lehmann, Grenzach-Wyhlen, DE;

Nigel John Mouncey, Binningen, CH;

Markus Wyss, Liestal, CH;

Assignee:

DSM IP Assets B.V., Te Heerlen, NL;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 17/00 (2006.01); C12P 21/04 (2006.01); C07H 21/04 (2006.01); C12N 9/14 (2006.01); C12N 15/00 (2006.01); C12N 1/20 (2006.01); C12Q 1/00 (2006.01); C12Q 1/68 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to modified GTP cyclohydrolase II enzymes that display increased specific activity, and to polynucleotides encoding them. The invention further pertains to vectors comprising these polynucleotides and host cells containing such vectors. The invention provides a method for producing the modified enzyme and a method for producing riboflavin, a riboflavin precursor, FMN, FAD, or a derivative thereof.


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