The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 02, 2011
Filed:
Mar. 25, 2003
Hilmar Meek Warenius, Heswell, GB;
Philip Spencer Rudland, Liverpool, GB;
Laurence Anthony Seabra, Heswell, GB;
Hilmar Meek Warenius, Heswell, GB;
Philip Spencer Rudland, Liverpool, GB;
Laurence Anthony Seabra, Heswell, GB;
Theryte Ltd., Liverpool, GB;
Abstract
Provided is a method for screening for effective agents for the treatment of cancer which method comprises selecting a putative agent that is likely to disrupt a function mediated by a critical normal gene product, which function is required for the successful division and continued cell survival of cancer cells, and which function is not required for the successful division and continued cell survival of control cells, treating a cancer cell sample and a control cell sample with a purative agent and determining the cytotoxic effect of, and/or the growth inhibitory effect of the putative agent on these samples, and identifying an effective agent as an agent which is more cytotoxic to, and/or more inhibiting to the growth of the cancer cell sample than the control cell sample. This invention further provides an effective agent identified by this screening method and a method of treating a cancer patient with such an agent.