The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 26, 2011

Filed:

May. 02, 2008
Applicants:

Christopher W. Grote, Webster Groves, MO (US);

Peter X. Wang, Chesterfield, MO (US);

Tao Jiang, St. Louis, MO (US);

Gary L. Cantrell, Troy, IL (US);

Frank W. Moser, Arnold, MO (US);

Catherine E. Thomasson, Webster Groves, MO (US);

Inventors:

Christopher W. Grote, Webster Groves, MO (US);

Peter X. Wang, Chesterfield, MO (US);

Tao Jiang, St. Louis, MO (US);

Gary L. Cantrell, Troy, IL (US);

Frank W. Moser, Arnold, MO (US);

Catherine E. Thomasson, Webster Groves, MO (US);

Assignee:

Mallinckrodt Inc., Hazelwood, MO (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 489/08 (2006.01); C07D 489/02 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention is directed to the conversion of a 6-keto morphinan to a 6-alpha-hydroxy morphinan in the presence of a ruthenium, rhodium, or iridium asymmetric catalyst and a hydrogen source.


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