The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 26, 2011
Filed:
Oct. 18, 2007
Shang-cheng Hung, Taipei, TW;
Cheng-chung Wang, Taichung, TW;
Jinq Chyi Lee, Hsinchu, TW;
Shun Yuan Luo, Taichung, TW;
Suvarn Subhash Kulkarni, Mumbai, IN;
Yu Wen Huang, Rochester, NY (US);
Chia Chen Lee, Rochester, NY (US);
Ken Lien Chang, Taipei, TW;
Shang-Cheng Hung, Taipei, TW;
Cheng-Chung Wang, Taichung, TW;
Jinq Chyi Lee, Hsinchu, TW;
Shun Yuan Luo, Taichung, TW;
Suvarn Subhash Kulkarni, Mumbai, IN;
Yu Wen Huang, Rochester, NY (US);
Chia Chen Lee, Rochester, NY (US);
Ken Lien Chang, Taipei, TW;
National Tsing Hua University, Hsinchu, TW;
Abstract
A method for preparing hexose derivatives comprises the steps of providing a silylated hexose, treating the silylated hexose with a first carbonyl compound in the presence of a catalyst to form an ketalized hexose, treating the ketalized hexose with a second carbonyl compound followed by treating with a first reductant to form an etherized hexose, and converting the etherized hexose into a target hexose derivative, which can be 2-alcohol hexose, 3-alcohol hexose, 4-alcohol hexose, or a 6-alcohol hexose. In particular, the present invention can prepare the hexose derivatives with highly regioselective scheme to protect individual hydroxyls of monosaccharide units and install an orthogonal protecting group pattern in a one-pot manner.