The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 26, 2011

Filed:

Nov. 13, 2006
Applicants:

Thomas J. Gardella, Needham, MA (US);

Henry M. Kronenberg, Belmont, MA (US);

John T. Potts, Newton, MA (US);

Harald Jüppner, Cambridge, MA (US);

Inventors:

Thomas J. Gardella, Needham, MA (US);

Henry M. Kronenberg, Belmont, MA (US);

John T. Potts, Newton, MA (US);

Harald Jüppner, Cambridge, MA (US);

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/08 (2006.01); A61K 38/10 (2006.01); A61K 38/22 (2006.01); A61K 51/00 (2006.01); A61K 103/10 (2006.01); A61P 19/08 (2006.01);
U.S. Cl.
CPC ...
Abstract

Novel parathyroid hormone peptide (PTH) and parathyroid hormone related peptide (PTHrP) or derivatives thereof which are biologically active are disclosed, as are pharmaceutical compositions containing such peptides, and synthetic and recombinant methods for producing such peptides. Also disclosed are methods for treating mammalian conditions characterized by decreases in bone mass using therapeutically effective pharmaceutical compositions containing such peptides. Also disclosed are methods for screening candidate compounds of the invention for antagonistic or agonistic effects on parathyroid hormone receptor action. Also disclosed are diagnostic and therapeutic methods of such compounds.


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