The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 26, 2011

Filed:

May. 03, 2007
Applicants:

Gennadiy M. Yershov, Willowbrook, IL (US);

Alexander Kukhtin, Lockport, IL (US);

Boris K. Chernov, Burr Ridge, IL (US);

Julia B. Golova, Willowbrook, IL (US);

Darrell P. Chandler, Manchester, MI (US);

Inventors:

Gennadiy M. Yershov, Willowbrook, IL (US);

Alexander Kukhtin, Lockport, IL (US);

Boris K. Chernov, Burr Ridge, IL (US);

Julia B. Golova, Willowbrook, IL (US);

Darrell P. Chandler, Manchester, MI (US);

Assignee:

UChicago Argonne, LLC, Chicago, IL (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C40B 60/10 (2006.01);
U.S. Cl.
CPC ...
Abstract

Multiplexed affinity purification and thermal dissociation prior to biochip hybridization simplifies uncharacterized sample admixtures, thereby minimizing or eliminating sample interferents, improving hybridization specificity on a microarray detector, and minimizing or eliminating the need for post-hybridization thermal dissociation analysis. An integrated thermo-affinity sample preparation sub-circuit for sample purification and enrichment is described that is consistent with a field-portable form factor and analytical processes. Thermo-affinity sample preparation on model admixtures of varying complexity was efficacious.


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