The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 19, 2011
Filed:
Feb. 01, 2008
John D. Shaughnessy, Little Rock, AR (US);
Bart Barlogie, Little Rock, AR (US);
Fenghuang Zhan, Little Rock, AR (US);
John D. Shaughnessy, Little Rock, AR (US);
Bart Barlogie, Little Rock, AR (US);
Fenghuang Zhan, Little Rock, AR (US);
Board of Trustees of the University of Arkansas, Little Rock, AR (US);
Abstract
Provided herein is a method for gene expression profiling multiple myeloma patients into distinct subgroups via DNA hybridization and hierarchical clustering analysis of the hybridization data where the results may further be used to identify therapeutic gene targets. Also provided is a method for controlling bone loss in an individual via pharmacological inhibitors of DKK1 protein. In addition provided herein is a method for diagnosing multiple myeloma using a 15-gene model that classifies myeloma into groups 1-7.