The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 19, 2011

Filed:

Aug. 12, 2004
Applicants:

Brett P. Monia, Carlsbad, CA (US);

Kenneth W. Dobie, Del Mar, CA (US);

Susan M. Freier, San Diego, CA (US);

Ian Popoff, Encinitas, CA (US);

James G. Karras, San Marcos, CA (US);

Inventors:

Brett P. Monia, Carlsbad, CA (US);

Kenneth W. Dobie, Del Mar, CA (US);

Susan M. Freier, San Diego, CA (US);

Ian Popoff, Encinitas, CA (US);

James G. Karras, San Marcos, CA (US);

Assignee:

Isis Pharmaceuticals, Inc., Carlsbad, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07H 21/00 (2006.01); C07H 21/02 (2006.01); C12N 15/11 (2006.01); A61K 48/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

Compositions and methods for the treatment and diagnosis of diseases or conditions amenable to treatment through modulation of expression of a gene encoding a p38 mitogen-activated protein kinase (p38 MAPK) are provided. Methods for decreasing airway hyperresponsiveness or airway inflammation in an animal are also provided.


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