The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 19, 2011
Filed:
Aug. 26, 2006
Frank Zocher, Frankfurt am Main, DE;
Christoph Hoh, Frankfurt am Main, DE;
Rainer Mueller, Penzberg, DE;
Erhard Kopetzki, Penzberg, DE;
Frank Geipel, Penzberg, DE;
Stephan Glaser, Seeshaupt, DE;
Frank Zocher, Frankfurt am Main, DE;
Christoph Hoh, Frankfurt am Main, DE;
Rainer Mueller, Penzberg, DE;
Erhard Kopetzki, Penzberg, DE;
Frank Geipel, Penzberg, DE;
Stephan Glaser, Seeshaupt, DE;
Sanofi-Aventis Deutschland GmbH, , DE;
Roche Diagnostics Operations, Inc., Indianapolis, IN (US);
Abstract
The present invention relates to the production of a variant of recombinant trypsin with increased substrate specificity for arginine versus lysine in non-animal host organisms. Moreover, the present invention relates to a variant of recombinant trypsin and their production. Also provided are use of recombinant porcine pancreatic trypsin variants for cleavage of precursors of insulins, and kits containing the variant of trypsin.