The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 19, 2011
Filed:
Aug. 01, 2003
Applicants:
Heng Wang, Beijing, CN;
Qiliang Cai, Beijing, CN;
Inventors:
Heng Wang, Beijing, CN;
Qiliang Cai, Beijing, CN;
Assignees:
Institute of Basic Medical Sciences, Beijing, CN;
Chinese Academy of Medical Sciences, Beijing, CN;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/28 (2006.01); C12P 21/02 (2006.01);
U.S. Cl.
CPC ...
Abstract
The invention relates to a method for preparing polyepitope chimeric gene vaccines, designated as Epitopes Assemble Library Immunization (EALI). It involves the construction of expression libraries of polyepitope chimeric genes with different sizes and lengths using gene shuffling and random assembly so as to screen polyepitope chimeric gene vaccines. Immunization of the body with the gene libraries of the invention results in the induction of high level of specific antibodies and specific types of cytokines, and protection on the body.