The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 19, 2011
Filed:
Apr. 25, 2007
Adnan M. M. Mjalli, Oak Ridge, NC (US);
Robert Rothlein, Summerfield, NC (US);
YE Edward Tian, Jamestown, NC (US);
Jeffrey C. Webster, Jamestown, NC (US);
Eric J. Benjamin, Jamestown, NC (US);
Adnan M. M. Mjalli, Oak Ridge, NC (US);
Robert Rothlein, Summerfield, NC (US);
Ye Edward Tian, Jamestown, NC (US);
Jeffrey C. Webster, Jamestown, NC (US);
Eric J. Benjamin, Jamestown, NC (US);
Transtech Pharma, Inc., High Point, NC (US);
Abstract
Disclosed are RAGE fusion proteins comprising RAGE polypeptide sequences linked to a second, non-RAGE polypeptide. The RAGE fusion protein may utilize a RAGE polypeptide domain comprising a RAGE ligand binding site and an interdomain linker directly linked to the N-terminus of an immunoglobulin C2 domain. Also disclosed are RAGE fusion protein formulations and the use of the RAGE fusion proteins and RAGE fusion protein formulations as therapeutics for RAGE-mediated pathologies.