The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 19, 2011
Filed:
Dec. 21, 2001
Bernhard K. Mueller, Neustadt, DE;
Philippe P. Monnier, Toronto, CA;
Paolo Macchi, Tubingen, DE;
Friedrich Bonhoeffer, Tubingen, DE;
Bernd Stahl, Tubingen, DE;
Matthias Mann, Odense M, DK;
Jens S. Anderson, Odense SO, DK;
Bernhard K. Mueller, Neustadt, DE;
Philippe P. Monnier, Toronto, CA;
Paolo Macchi, Tubingen, DE;
Friedrich Bonhoeffer, Tubingen, DE;
Bernd Stahl, Tubingen, DE;
Matthias Mann, Odense M, DK;
Jens S. Anderson, Odense SO, DK;
Abstract
The present invention relates to the use of a modulator of a polypeptide having or comprising an amino acid sequence as disclosed herein or of a functional fragment or derivative thereof or of a polynucleotide encoding said polypeptide or fragment or derivative for the preparation of a pharmaceutical composition for preventing, alleviating or treating diseases or conditions associated with the degeneration or injury of vertebrate nervous tissue, associated with seizures or associated with angiogenic disorders or disorders of the cardio-vascular system. Furthermore, the invention provides for the use of a modulator of a polypeptide having or comprising said amino acid sequence of a functional fragment or derivative thereof or of a polynucleotide encoding said polypeptide or fragment or derivative for the preparation of a pharmaceutical composition for preventing, alleviating or treating diseases or conditions associated with the degeneration or injury of vertebrate nervous tissue, associated with angiogenic disorders or disorders of the cardio-vascular system. In addition the invention provides for the use of said polypeptide or said functional fragment or derivative thereof for the preparation of a pharmaceutical composition for preventing or treating tumor growth or formation of tumor metastases or as a marker of stem cells.