The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 19, 2011
Filed:
Mar. 01, 2008
Lukas C. Amler, Foster City, CA (US);
Merrill Birkner, Menlo Park, CA (US);
Chin-yu Lin, Redwood City, CA (US);
Joachim Moecks, Mannheim, DE;
Andreas Strauss, Penzberg, DE;
Lukas C. Amler, Foster City, CA (US);
Merrill Birkner, Menlo Park, CA (US);
Chin-Yu Lin, Redwood City, CA (US);
Joachim Moecks, Mannheim, DE;
Andreas Strauss, Penzberg, DE;
Genentech, Inc., South San Francisco, CA (US);
Hoffmann-La Roche Inc., Nutley, NJ (US);
Abstract
The present application describes the use of low HER3 as a selection criterion for treating patients with a HER inhibitor, such as pertuzumab. It also describes the use of high HER2:HER3 ratio as a selection criterion for treating cancer patients, such as ovarian cancer patients, with a HER inhibitor, such as pertuzumab. In addition, the application describes the use of high HER3 as a selection criterion for treating cancer patients with a chemotherapeutic agent, for instance gemcitabine.