The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 12, 2011
Filed:
Mar. 17, 2010
Dalton King, Hamden, CT (US);
Zhaoxing Meng, Middletown, CT (US);
Ivar M. Mcdonald, East Haddam, CT (US);
Richard E. Olson, Orange, CT (US);
John E. Macor, Guilford, CT (US);
Dalton King, Hamden, CT (US);
Zhaoxing Meng, Middletown, CT (US);
Ivar M. McDonald, East Haddam, CT (US);
Richard E. Olson, Orange, CT (US);
John E. Macor, Guilford, CT (US);
Bristol-Myers Squibb Company, Princeton, NJ (US);
Abstract
Disclosed are compounds, pharmaceutical compositions containing the compounds, methods for using the compounds and processes for making the compounds. More specifically, the disclosure relates to alpha-(N-benzenesulfonamido)cycloalkyl compounds that may inhibit one or both of: (i) the functioning of a γ-secretase enzyme; or (ii) the production of β-amyloid. Such compounds may be beneficial in the treatment of Alzheimer's disease and other conditions. Representative compounds have the following formula I: wherein: A, R, and Rare described herein.