The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 12, 2011
Filed:
Nov. 24, 2003
Jacques P. Dumas, Bethany, CT (US);
Stephen J. Boyer, Hilden, DE;
Julie A. Dixon, Bethany, CT (US);
Teddy K. Joe, San Francisco, CA (US);
Harold C. E. Kluender, Trumbull, CT (US);
Wendy Lee, Hamden, CT (US);
Dhanapalan Nagarathnam, Bethany, CT (US);
Robert N. Sibley, North Haven, CT (US);
Ning Su, Hamden, CT (US);
Jacques P. Dumas, Bethany, CT (US);
Stephen J. Boyer, Hilden, DE;
Julie A. Dixon, Bethany, CT (US);
Teddy K. Joe, San Francisco, CA (US);
Harold C. E. Kluender, Trumbull, CT (US);
Wendy Lee, Hamden, CT (US);
Dhanapalan Nagarathnam, Bethany, CT (US);
Robert N. Sibley, North Haven, CT (US);
Ning Su, Hamden, CT (US);
Bayer Healthcare LLC, Tarrytown, NY (US);
Abstract
Substituted and pyridines and pyridazines having angiogenesis inhibiting activity and the generalized structural formula wherein the ring containing A, B, D, E, and L is phenyl or a nitrogen-containing heterocycle; groups X and Y may be any of a variety of defined linking units; Rand Rmay be defined independent substituents or together may be a ring-defining bridge; ring J may be an aryl, pyridyl, or cycloalkyl group; and G groups may be any of a variety of defined substituents. Pharmaceutical compositions containing these materials, and methods of treating a mammal having a condition characterized by abnormal angiogenesis or hyperpermiability processes using these materials are also disclosed.