The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 12, 2011
Filed:
Nov. 26, 2008
Sven Weiler, Lorrach, DE;
Leo Widler, Muenchenstein, CH;
Jean Michel Rondeau, Rixheim, FR;
Simona Cotesta, Basel, CH;
Wolfgang Jahnke, Lorrach, DE;
Sven Weiler, Lorrach, DE;
Leo Widler, Muenchenstein, CH;
Jean Michel Rondeau, Rixheim, FR;
Simona Cotesta, Basel, CH;
Wolfgang Jahnke, Lorrach, DE;
Novartis AG, Basel, CH;
Abstract
C-C-Alkyl-substituted [(imidazol-1-yl)-1-hydroxy-1-phosphono-ethyl]-phosphonic acids, as well as methods or processes for their manufacture, their use in the manufacture of pharmaceutical formulations, their use in the treatment of diseases, methods of using them in the treatment of diseases, pharmaceutical formulations encompassing them and/or the compounds for use in the treatment of diseases, are described. The compounds are able to inhibit excessive or inappropriate bone resorption and for the treatment of other diseases which are caused by excessive prenylation of target proteins, such as Hutchinson-Gilford progeria syndrome. The compounds are of the formula I, wherein one of Rand Ris hydrogen and the other is C-C-alkyl that is branched or unbranched, and can be in free form, in the form of an ester, and/or of a salt.