The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 12, 2011

Filed:

Oct. 26, 2007
Applicants:

Joan C. Egrie, Newbury Park, CA (US);

Steven G. Elliott, Newbury Park, CA (US);

Jeffrey K. Browne, Camarillo, CA (US);

Karen C. Sitney, Studio City, CA (US);

Inventors:

Joan C. Egrie, Newbury Park, CA (US);

Steven G. Elliott, Newbury Park, CA (US);

Jeffrey K. Browne, Camarillo, CA (US);

Karen C. Sitney, Studio City, CA (US);

Assignee:

Amgen Inc., Thousand Oaks, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 14/505 (2006.01); A61K 38/16 (2006.01);
U.S. Cl.
CPC ...
Abstract

Methods for increasing and maintaining hematocrit in a mammal comprising administering a hyperglycosylated analog of erythropoietin are disclosed. An analog may be administered less frequently than an equivalent molar amount of recombinant human erythropoietin to obtain a comparable target hematocrit and treat anemia. Alternatively, a lower molar amount of a hyperglycosylated analog may be administered to obtain a comparable target hematocrit and treat anemia. Also disclosed are new hyperglycosylated erythopoietin analogs, methods of production of the analogs, and compositions comprising the analogs.


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