The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 05, 2011
Filed:
Jul. 05, 2006
Rajendra Narayanrao Kankan, Maharashtra, IN;
Dharmaraj Ramachandra Rao, Maharashtra, IN;
Manjinder Singh Phull, Maharashtra, IN;
Ashwini Sawant, Maharashtra, IN;
Dilip Ramdas Birari, Maharashtra, IN;
Rajendra Narayanrao Kankan, Maharashtra, IN;
Dharmaraj Ramachandra Rao, Maharashtra, IN;
Manjinder Singh Phull, Maharashtra, IN;
Ashwini Sawant, Maharashtra, IN;
Dilip Ramdas Birari, Maharashtra, IN;
Cipla Limited, Mumbai, IN;
Abstract
A process for the synthesis of trandolapril which comprises condensing N—[I—(S)-ethoxycarbonyl-3-phenylpropyl]-L-alanine N-carboxyanhydride with trans octahydro-1H-indole-2-carboxylic acid in a first organic solvent comprising a water immiscible inert organic solvent and in the presence of a base, and isolating trandolapril from a second organic solvent. N-[1-(S)-ethoxycarbonyl-3-phenylpropyl]-L-alanine N-carboxyanhydride may also be condensed with (2S,3aR,7aS) octahydro-1H-indole-2-carboxylic acid in a first organic solvent and in the presence of a base, and trandolapril isolated. There is also provided a process for the resolution of racemic trans octahydro-1H-indole-2-carboxylc acid.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile