The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 05, 2011

Filed:

May. 16, 2006
Applicants:

Satoshi Omura, Tokyo, JP;

Hiroshi Tomoda, Tokyo, JP;

Yong-pil Kim, Chiba, JP;

Hideaki Hanaki, Kanagawa, JP;

Atsuko Matsumoto, Tokyo, JP;

Yoko Takahashi, Tokyo, JP;

Inventors:

Satoshi Omura, Tokyo, JP;

Hiroshi Tomoda, Tokyo, JP;

Yong-pil Kim, Chiba, JP;

Hideaki Hanaki, Kanagawa, JP;

Atsuko Matsumoto, Tokyo, JP;

Yoko Takahashi, Tokyo, JP;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07H 15/20 (2006.01); C07H 15/22 (2006.01); C07C 61/12 (2006.01);
U.S. Cl.
CPC ...
Abstract

A microorganism represented by a strain K04-0144 belonging tosp. having ability to produce K04-0144 substance is cultured in the medium, and the isolated K04-0144A substance, K04-0144B substance and K04-0144C substance therefrom have strong antibacterial activities against Gram-positive bacteria including methicillin-resistant(MRSA), consequently these are useful as the therapeutic agents for infectious disease caused by MRSA as well as infectious diseases caused by multidrug including β-lactam antibiotics resistant bacteria. Further, similarly, since the novel K04-0144D substance isolated from the cultured liquid has the action for enhancing the effect of β-lactam antibiotics, which are utilized as the antibacterial agents, in combination with them, it is useful as the therapeutic agent for infectious diseases caused by methicillin-resistant(MRSA) and multidrug including β-lactam antibiotics resistant bacteria.


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