The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 05, 2011

Filed:

Dec. 15, 2008
Applicants:

Ahmed Abouabdellah, Thiais, FR;

Antonio Almario Garcia, Chatenay Malabry, FR;

Christian Hoornaert, Antony, FR;

Tak Adrien LI, Fontenay aux Roses, FR;

Inventors:

Ahmed Abouabdellah, Thiais, FR;

Antonio Almario Garcia, Chatenay Malabry, FR;

Christian Hoornaert, Antony, FR;

Tak Adrien Li, Fontenay aux Roses, FR;

Assignee:

Sanofi-Aventis, Paris, FR;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 241/04 (2006.01); C07D 295/00 (2006.01); A61K 31/4965 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention comprises alkylpiperazine- and alkylhomopiperazine carboxylates and their derivatives, methods for their preparation and the therapeutic use thereof as fatty acid amido hydrolase (FAAH) enzyme inhibitors. These derivatives exert various pharmacological activities by interacting, inter alia, with cannabinoid and vanilloid receptors. By inhibiting the metabolic activity of the FAAH enzyme, compounds often responsible for the onset of disease and other pathological conditions are not generated and the incidence of the disease is greatly reduced.


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