The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 05, 2011

Filed:

Feb. 15, 2008
Applicants:

Yun-long LI, Newark, DE (US);

Jincong Zhuo, Marcus Hook, PA (US);

David M. Burns, Philadelphia, PA (US);

Wenqing Yao, Kennett Square, PA (US);

Ravi Kumar Jalluri, Avondale, PA (US);

Inventors:

Yun-Long Li, Newark, DE (US);

Jincong Zhuo, Marcus Hook, PA (US);

David M. Burns, Philadelphia, PA (US);

Wenqing Yao, Kennett Square, PA (US);

Ravi Kumar Jalluri, Avondale, PA (US);

Assignee:

Incyte Corporation, Wilmington, DE (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/497 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides compounds of the formula: its enantiomers, diastereomers, racemic mixtures thereof, prodrugs, crystalline forms, non-crystalline forms, amorphous forms thereof, solvates thereof, metabolites thereof, and pharmaceutically acceptable salts, wherein the ring A substituent groups are fully defined in the following disclosure. The compounds of formula are inhibitors of metalloproteases such as matrix metalloproteases and sheddases, and are useful in treating diseases such as rheumatoid arthritis, psoriasis, neoplastic diseases, allergies and all those diseases wherein inhibition of MMPs is desirable.


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