The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 7972837 B1

PDF
Full Text
Expired
Date of Patent:
Jul. 05, 2011

Filed:

Mar. 05, 2008
Applicants:

Helen Lee, Cambridge, GB;

Ling Huang, Cambridge, GB;

Magda Anastassova Dineva, Cambridge, GB;

Hsiang Yun HU, Union City, CA (US);

Inventors:

Helen Lee, Cambridge, GB;

Ling Huang, Cambridge, GB;

Magda Anastassova Dineva, Cambridge, GB;

Hsiang Yun Hu, Union City, CA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/53 (2006.01);
U.S. Cl.
CPC ...
Abstract

Dipstick tests for detecting analyte are described. In a preferred embodiment, a multiple biotinylated antibody capable of binding analyte is bound to an anti-biotin antibody labeled with colloidal gold and wicked up the dipstick with test solution thought to contain analyte. Complex formed between analyte, biotinylated anti-analyte antibody, and colloidal gold labeled anti-biotin antibody is captured at a capture zone of the dipstick. Presence of colloidal gold label at the capture zone indicates the presence of analyte in the test solution. The sensitivity of analyte detection using such methods is an order of magnitude higher than for comparable methods in which biotinylated anti-analyte antibody bound to analyte is wicked up the dipstick in a first step, and a colloidal gold labeled anti-biotin antibody is wicked up the dipstick in a separate step. Kits for performing the tests of the invention are also described.


Find Patent Forward Citations

Lee, Helen. (2011). Signal enhancement system with multiple labeled-moieties (U.S. Patent No. 7972837). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/7972837

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