The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 28, 2011
Filed:
Dec. 06, 2007
David G. Hangauer, East Amherst, NY (US);
Fengzhi LI, Buffalo, NY (US);
Taher Hegab, Fresno, CA (US);
Xiang Ling, Snyder, NY (US);
David G. Hangauer, East Amherst, NY (US);
Fengzhi Li, Buffalo, NY (US);
Taher Hegab, Fresno, CA (US);
Xiang Ling, Snyder, NY (US);
The Research Foundation of State University of New York, Amherst, NY (US);
Health Research Inc., Buffalo, NY (US);
Abstract
Disclosed are compounds having the formula: wherein Zis an alkylene moiety; Q is a carboxylic acid derivative; and Rand Rare the same or different and are selected from the group consisting of alkyl, aryl, alkylcarbonyl, arylcarbonyl, hydroxycarbonyl, and alkoxycarbonyl or Rand R, taken together with the nitrogen atom to which they are bound, form a ring. Also disclosed are compounds having the formula: wherein Zis an alkylene moiety; Q is a carboxylic acid derivative; and Ris selected from the group consisting of alkyl and aryl. The compounds can be used to modulate cell proliferation and/or apoptosis, for example, in the treatment of cancers and other proliferative diseases, disorders, and conditions.