The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 28, 2011

Filed:

Dec. 20, 2005
Applicants:

Mark C. Sleevi, Midlothian, VA (US);

Glen L. Kelley, Glen Allen, VA (US);

Inventors:

Mark C. Sleevi, Midlothian, VA (US);

Glen L. Kelley, Glen Allen, VA (US);

Assignee:

Insmed Incorporated, Glen Allen, VA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); A61K 38/30 (2006.01); C07K 14/435 (2006.01); C07K 14/65 (2006.01);
U.S. Cl.
CPC ...
Abstract

Complexes of IGF-I and IGFBP-3 with new levels of purity are provided. Chromatographic techniques have been developed that remove contaminants, such as mass and charge variants of IGFBP-3. The new techniques enable the production of high-quality pharmaceutical compositions comprising IGF-I/IGFBP-3 complexes.


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