The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 28, 2011

Filed:

Feb. 14, 2005
Applicants:

Ha-soon Choi, San Diego, CA (US);

Zhicheng Wang, San Diego, CA (US);

Nathanael Schiander Gray, Boston, MA (US);

Xiang-ju Gu, San Diego, CA (US);

Xiaohui He, San Diego, CA (US);

Yun He, San Diego, CA (US);

Tao Jiang, San Diego, CA (US);

Yi Liu, San Diego, CA (US);

Wendy Richmond, San Diego, CA (US);

Taebo Sim, Chestnut Hill, MA (US);

Kunyong Yang, San Diego, CA (US);

Inventors:

Ha-Soon Choi, San Diego, CA (US);

Zhicheng Wang, San Diego, CA (US);

Nathanael Schiander Gray, Boston, MA (US);

Xiang-ju Gu, San Diego, CA (US);

Xiaohui He, San Diego, CA (US);

Yun He, San Diego, CA (US);

Tao Jiang, San Diego, CA (US);

Yi Liu, San Diego, CA (US);

Wendy Richmond, San Diego, CA (US);

Taebo Sim, Chestnut Hill, MA (US);

Kunyong Yang, San Diego, CA (US);

Assignee:

Novartis AG, Basel, CH;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 487/04 (2006.01); A61K 31/519 (2006.01); A61P 35/00 (2006.01); A61P 37/06 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated kinase activity, particularly diseases or disorders that involve abnormal activation of the FAK, Abl, BCR-Abl, PDGF-R, c-Kit, NPM-ALK, Flt-3, JAK2 and c-Met kinases.


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