The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 28, 2011

Filed:

Apr. 23, 2007
Applicants:

Kenji Negoro, Tokyo, JP;

Fumiyoshi Iwasaki, Tokyo, JP;

Kei Ohnuki, Tokyo, JP;

Toshio Kurosaki, Tokyo, JP;

Yasuhiro Yonetoku, Tokyo, JP;

Norio Asai, Tokyo, JP;

Shigeru Yoshida, Tokyo, JP;

Takatoshi Soga, Tokyo, JP;

Inventors:

Kenji Negoro, Tokyo, JP;

Fumiyoshi Iwasaki, Tokyo, JP;

Kei Ohnuki, Tokyo, JP;

Toshio Kurosaki, Tokyo, JP;

Yasuhiro Yonetoku, Tokyo, JP;

Norio Asai, Tokyo, JP;

Shigeru Yoshida, Tokyo, JP;

Takatoshi Soga, Tokyo, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/506 (2006.01); A61K 31/4439 (2006.01); A61K 31/4245 (2006.01); C07D 413/12 (2006.01); C07D 271/07 (2006.01);
U.S. Cl.
CPC ...
Abstract

A compound which can be used as a pharmaceutical, particularly a insulin secretion promoter or a agent for preventing/treating disease in which GPR40 is concerned such as diabetes or the like, is provided. It was found that an oxadiazolidinedione compound which is characterized by the possession of a benzyl or the like substituent binding to the cyclic group via a linker at the 2-position of the oxadiazolidinedione ring, or a pharmaceutically acceptable salt thereof, has excellent GPR40 agonist action. In addition, since the oxadiazolidinedione compound of the present invention showed excellent insulin secretion promoting action and blood glucose level-lowering action, it is useful as an insulin secretion promoter or an agent for preventing/treating diabetes.


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